plot(data,#,size,#)

7f5b9f3a-a0f5-4236-836e-b8984f49edb3 31 4 5 decimal

&[DATE] &[TIME] - &[FILENAME]

plot(data,#,size,#)

data char size clr plot k 1 data rows range r3 k el char : r4 k el size : r5 k el clr : 31 line for data r3 r4 r5 augment 21 line :

data 3 0.164 4.51 0.133 4.653 0.11 4.9 0.063 4.906 0.05 4.977 0.051 5.1 0.039 5.178 0.038 5.43 0.024 5.463 0.023 5.47 0.022 6.151 0.004 6.93 0.002 7.317 0.001 7.487 0.001 7.598 0.001 7.757 0.001 7.929 0.001 8.187 0 8.465 0202 mat :

NOT compatible Genfit

x β f β 1 el 1 x β 2 el - β 3 el / (β 4 el^+ / :

β 0.164 3.123 1.674 6.565 41 mat :

XY data . 10 black plot :

x β D x β f x diff : inflexion 4.7205 : 21 sys

inflexion β f inflexion β D 21 mat 0.0945 0.1646 - 21 mat

Transmute model for fitting unknown Pharmacokinetics.

x β f x β D XY inflexion inflexion β f + 20 red 1 5 mat 4 1 sys Max/Min Golden ratio

Code adapted from Valery Ochov Mathcad 11 f a b test TOL Extrema a b G 32 / b * 12 / a * - 12 / 5 sqrt * a b - (* + : y1 y2 ≥ (max in range ≡ y1 y2 ≤ (min in range ≡ x1 a b G eval : y1 x1 f eval : x2 b a G eval : y2 x2 f eval : 41 line iter 0 : iter 1000 < a b - abs TOL ≤ break test b x2 : x2 x1 : y2 y1 : x1 a b G eval : y1 x1 f eval : 51 line a x1 : x1 x2 : y1 y2 : x2 b a G eval : y2 x2 f eval : 51 line if iter iter 1 + : 21 line if while a b + 2 / iter 21 mat 71 line :

1. All modules/functions in "Symbolic" optimiz. 2. Once in target: shrink the range 3. respect the search y1≥y2≡"max in range" y1≤y2≡"min in range"

x f x 4^2 x 3^* - 7 x 2^* - 2 - :

X f 1.5 - 1 - y1 y2 ≤ 1012 -^Extrema 1 el f 0.5 - 0.5 y1 y2 ≥ 1012 -^Extrema 1 el f 2.5 3 y1 y2 ≤ 1012 -^Extrema 1 el 31 mat :

X 1.265564 - 2.816018 108 -^* - 2.765564 31 mat

x f X 1 el X 1 el f + 15 red X 2 el X 2 el f + 15 red X 3 el X 3 el f + 15 red 3 5 mat 2 1 sys

recast 'f' style Golden ratio x f x β D :

Xpharma q 45 y1 y2 ≤ 1012 -^Extrema 1 el :

Xpharma 4.7205